Cannabis is a known medicinal compound that has a powerful anti-inflammatory effect. Its ability to reduce inflammation, more particularly in MS cases have led to the founding and the proliferation of Sativex, the first market-approved medicine made by GW Pharmaceutical.
Medical marijuana can act as an effective treatment for managing MS-related pain. A study has concluded that cannabis is more effective than a placebo in reducing sleep disturbances and pain. Smoking marijuana produces the same desired effect on patients who are suffering from multiple sclerosis.
Cannabis plays an active role in reducing muscle spasticity and muscle spasms by limiting the immune response. A 2007 published review revealed how THC was better than CBD and dronabinol in managing the pain felt by MS sufferers.
Pain or stiffness is further reduced by cannabis' ability to limit the frequency of muscle spasticity and muscle spasms. In a gold standard clinical trial that has randomized, placebo controlled and double blind elements, 37 out of 50 patients showed definite mobility improvements and reduced muscle spasm frequency.
Depression is a common component in patients suffering from MS- clinical cases have documented over 50 percent of MS patients had experienced depression as a side effect. The reason for this could be due to the damage to the nerves controlling the patient's mood or as a side effect from various medications used. MS patients are also prone to other emotional dysfunction behaviors as a symptom.
More than 90 percent of MS patients in the UK and the US showed a positive effect in mood and emotional dysfunction when dosed with medical cannabis. The improvement in mood could be due to several factors, including reduced pain, muscle spasms or reduced damage to the nerves affecting the person's mood.
MS can also cause the patient to suffer faecal incontinence, constipation and abdominal pain. The use of medical marijuana has reduced the frequency and severity of constipation and faecal incontinence to about 30% and 44%, respectively.
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